The Multiple Sclerosis Discovery Forum (MSDF) is an online resource that aims to accelerate progress toward cures for multiple sclerosis and related disorders by sparking new ideas and catalyzing unforeseen connections. The site focuses attention on what is known and not yet known about the causes of these conditions, their pathological mechanisms, and potential ways to intervene. By communicating this information in a way that builds bridges among different disciplines, we will open new routes toward significant clinical advances. The podcast will include the latest in MS research news as well as one-on-one interviews with prominent MS researchers and clinicians. While the podcast is intended mainly for other researchers and clinicians, we welcome people with MS, their caregivers, and anyone else with an interest in multiple sclerosis and related disorders.